Scientist I, Cell and Molecular Biologist

Description:

AbbVie Oncology Discovery is seeking a highly motivated and experienced cancer cell biologist to support drug discovery projects in our in vitro cancer biology team with a focus on antibody-drug conjugates. The candidate will work closely with a team of experienced scientists to develop and optimize key pharmacological, biochemical and cell-based assays to support multiple programs.

Key Responsibilities:

• Design and execute in vitro studies to assess novel antibody-drug conjugates
• Analyze and interpret experiments and present data to the broader project team and group meetings. Propose relevant follow-up experiments as needed.
• Troubleshoot and/or optimize experimental procedures as needed to further the program goals.
• Contribute to the preparation of data packages for scientific publications, regulatory documents, and patent applications
• Work independently in a fast paced, multi-tasking environment as part of a diverse research team.
• Collaborate with cross-functional teams to advance programs from early discovery to preclinical development

Qualifications

Required:

• Bachelor’s Degree with 5 years of experience, or Master’s Degree with two years of experience in molecular/cellular biology, cancer biology, pharmacology or related discipline with significant research experience.
• Proficiency in tissue culture, cellular & biochemical in vitro assay development and molecular biology techniques (e.g Western blotting/WES, ELISA, proliferation assays, FACS, lentivirus)
• Background in drug discovery, pharmacology and assay development.
• Organizational skills and experience with computer programs, including Microsoft Excel, Powerpoint, GraphPad, FlowJo, etc.

Preferred:

• Understanding and application of methods of antibody characterization and/or antibody-drug conjugates.
• Knowledge and experience with a broad range of assays to characterize targeted protein degradation
• Familiarity and proficiency with available genomic/transcriptomic datasets (TCGA, DepMap, CCLE etc.)

Key Leadership Competencies:

• Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance.
• Learns fast, grasps the 'essence' and can change the course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces innovation and manages to reality.