Scientist I, Bioanalytical Research and Development

About the Team:  

The Analytical Development group within the Targeted LNP (tLNP) CMC Team at AbbVie is dedicated to advancing analytical capabilities for mRNA-lipid nanoparticle therapeutics. Our team supports drug substance (DS) and drug product (DP) manufacturing, drug product formulation by implementing state-of-the-art analytical methodologies to ensure the quality, safety and integrity of tLNP genetic medicines. Collaboration is at the core of what we do, as we work directly with CMC, drug product formulation, and external partners, and are currently growing a world-class team of scientists who will be instrumental in building the analytical toolbox necessary to deliver high-quality, innovative tLNP medicines to patients. 

About the Role 

We are seeking a highly motivated Associate Scientist II / Scientist I to join our Bioanalytical team. This is a hands-on laboratory role focused on the development, execution, and optimization of bioanalytical assays to characterize impurities and evaluate pharmaceutical products. The successful candidate will contribute to analytical testing and method development using a range of biochemical and molecular techniques, including ELISA, qPCR, colorimetric assays, and other protein characterization techniques. 

The person that will excel in this role has a desire to learn, attention to detail, and the ability to generate high-quality data in a collaborative environment. Experience with cell culture, particularly potency assays, is considered a bonus as well. 

Key Responsibilities 

• Perform routine and non-routine bioanalytical testing using ELISA, qPCR, colorimetric assays, and other protein characterization techniques. 
• Support characterization of product-related impurities and evaluation of pharmaceutical products to advance development activities. 
• Assist in the development, optimization, qualification, and troubleshooting of bioanalytical methods to meet project and departmental needs. 
• Analyze, interpret, and clearly document experimental data, observations, and conclusions in laboratory notebooks and electronic systems. 
• Prepare data summaries and present findings to team members and cross-functional partners. 
• Troubleshoot assay performance issues and help identify practical solutions to improve robustness, reproducibility, and efficiency. 
• Maintain laboratory equipment, reagents, consumables, and general laboratory organization to ensure smooth workflow and compliance. 
• Collaborate effectively with scientists and cross-functional colleagues to support timelines, project goals, and scientific decision-making. 
• Contribute to technical reports, study summaries, SOPs, and other scientific documentation as needed. 
• Follow applicable laboratory practices, safety procedures, and company standards for data integrity and documentation. 

Required Qualifications

• Associate Scientist II: Bachelor’s Degree in Biology, Biochemistry, Molecular Biology, Pharmaceutical Sciences, Analytical Chemistry, or a related scientific discipline, or equivalent education, with typically 3 or more years’ experience; or Master’s Degree or equivalent education (no additional experience). PhDs need not apply. 
• Scientist I: Bachelor’s degree in Biology, Biochemistry, Molecular Biology, Pharmaceutical Sciences, Analytical Chemistry or a related scientific discipline with typically 5 years of relevant experience; or Master’s degree in a related scientific discipline with typically 2 years of relevant experience. PhDs need not apply. 
• Hands-on experience with bioanalytical and biochemical assay techniques, including ELISA, qPCR, colorimetric assays, and Western blot. 
• Experience generating, analyzing, and interpreting experimental data with strong attention to detail. 
• Ability to troubleshoot assays and optimize experimental conditions. 
• Strong organizational skills with the ability to manage multiple experiments and priorities simultaneously. 
• Effective written and verbal communication skills. 
• Demonstrated ability to work both independently and collaboratively in a team-based environment. 
• Proficiency in maintaining accurate and complete scientific documentation. 

Preferred Qualifications

• Experience with cell culture techniques. 
• Experience developing or executing cell-based potency assays. 
• Familiarity with pharmaceutical or biologics development environments 
• Experience with method transfer to GMP environments