Scientist I/II, Biochemical & Cellular Assays (ON-SITE)

Purpose

Join our bioassay group in developing and executing a variety of in vitro bioassays, including biochemical and cellular assays. Execute novel scientific research or development that achieves projects and area goals. Investigate, identify, develop, and optimize new methods and techniques. Able to think critically and creatively across multiple disciplines. Demonstrated ability to solve research problems with experience in standard biochemical and cellular assays including assay development, optimization, and troubleshooting. Able to analyze and critically interpret and report data and research conclusions.

Responsibilities

• Develop in vitro assays, screening strategies, mechanistic studies, deliver high quality data from validated screens to drive lead series identification and lead optimization. The successful candidate will develop disease-relevant phenotypic assays using complex cellular models such as primary and stem cells and elucidate mechanism of action of molecules.
• Proficiency with multiple assay formats in higher throughput format
• Engage and collaborate with multiple disease area teams and make substantial contributions to the conception and execution of screens including mechanism of action studies within strict time and quality tolerances.
• Collaborate actively within the group and cross functional team to execute projects and coordinate discovery efforts.
• Maintain cutting-edge awareness of technical developments and scientific knowledge and proactively, applying these when appropriate.
• Effectively communicate results in presentations and written reports and actively participate in cross-functional teams.

• Scientist I: BS or equivalent education with typically 5 or more years of experience or MS or equivalent education with typically 2 or more years of experience.
• Scientist II:  BS or equivalent education with typically 7 or more years of experience or MS or equivalent education with typically 5 or more years of experience.
• Demonstrated experience in biochemical and cellular assays, such as protein-ligand binding, enzyme activity and functional cell assays.
• Skills in mammalian cell culture and cell transfection.
• Demonstrated ability to independently design, execute and interpret critical experiments to answer scientific questions.
• Demonstrated ability to learn, understand and master new experimental techniques..
• Ability to multi-task and work within timelines.
• Capable of working independently while contributing and participating in a team environment.
• Excellent oral and written communication skills.